A Peculiar Case of Pneumonia due to Mycoplasma pneumoniae in a Child with Cystic Fibrosis and Sensibilization to Aspergillus fumigatus

A Peculiar Case of Pneumonia due to Mycoplasma pneumoniae in a Child with Cystic Fibrosis and Sensibilization to Aspergillus fumigatus

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Aspergillus fumigatus plays a major role in pulmonary exacerbations in patients with cystic fibrosis.The most common A.fumigatus diseases are those based on immune-mediated response to A.fumigatus antigens; including allergic bronchopulmonary aspergillosis (ABPA).

In this condition; the presence of A.fumigatus in the lower respiratory tract triggers an IgE-mediated hypersensitivity response that causes airway inflammation; bronchospasms; and bronchiectasis.This case report describes a ten-year-old male patient suffering from cystic fibrosis (CF) Notepad in whom the diagnosis of VITAMIN C WITH ZINC ABPA occurred in association with pneumonia due to Mycoplasma pneumoniae more than two weeks after hospitalization.This case is a good example of how difficult the identification of ABPA in CF patients can be and highlights that ABPA can occur in association with co-infections due to other pathogens.

In order to avoid the risk of a late ABPA diagnosis, it is imperative that the diagnostic criteria guidelines are reviewed and standardized.